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capE [2017-8-11 16:0:3]
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capE [2017-8-11 16:0:3]

stimulates poly-gamma-glutamate production in the presence of zinc, also involved in extra-chromosomal DNA maintenance
locus
BSU35870
pI
6.49
mw
6.39 kDa
protein length
55 aa Sequence Blast
gene length
165 bp Sequence Blast
function
capsule synthesis
product
unknown
essential
no
synonyms
ywtC, pgsE, edmS
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.4|Capsule biosynthesis and degradation]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,697,639 → 3,697,806

    The protein

    Catalyzed reaction/ biological activity

  • stimulates poly-gamma-glutamate production in the presence of zinc [Pubmed|20812257]
  • also involved in extra-chromosomal DNA maintenance [Pubmed|23583563,21357437]

    • [SW|Domains]

  • N-terminal membrane-anchoring domain and a C-terminal assembly accelerator-like structure [Pubmed|23583563]

    • [SW|Localization]

  • cell membrane [Pubmed|23583563]

    • Expression and Regulation

    Operons

    genes
    [gene|86C05126ADBA22BB1771B1FA3D214B2E7A36311E|capB]-[gene|D66994D077D1382B88FF65075E44C2A31089548F|capC]-[gene|A696434A086A428D411CAF45B37CD8F82AC2503F|capA]-[gene|6B61DCE8D27776EBF942621D3AE90F410FD13F37|capE]
    description
    [Pubmed|11751809]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|19420703], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU]: activation, [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU]-P, [Pubmed|19734658], in [regulon|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU regulon]

    • additional information

  • expression of the operon is increased in '[protein|search|motA]' or '[protein|search|motB]' mutants due to increased [protein|search|DegU] phosphorylation [PubMed|24296669]
    • view in new tab

    References

    Reviews

  • 16689787

    • Original publications

  • 19420703,16233197,16267300,20564357,20564574,21357437,23583563,20812257,21965392,25843804